With the recent studies showing harm due to administration of other colloids there has been a natural interest in the extended use of albumin as a colloid. The safety issue of using albumin seems to have been resolved (with the exception of traumatic brain injury). Their use early on in acute illness seems questionable. However they may confer benefit in hypoalbuminaemic patients at risk of complications. The results of ongoing studies will hopefully offer further guidance. Future studies should aim to look at long-term follow-up, as there is always a risk when administering blood products. Health economics analysis should also be included as there are high costs associated with the use of albumin.
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